Dietary risk assessment based on the probability distribution of fluopyram residues
HAN Wen-hao1,2, ZHANG Ming-hao1,3, LIU Feng-jiao1, CHEN Yi-fu1, CHENG You-pu3, WU Yan-bing2, CHEN Zeng-long1
1. State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; 2. College of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, China; 3. College of Horticulture and Landscape Architecture, Tianjin Agricultural University, Tianjin 300384, China
Abstract：The exposure risk of fluopyram in cucumber was comprehensively evaluated for different dietary consumption groups in China based on its residual characteristics. A rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry method was developed for the determination of fluopicolide in cucumber, with limit of quantitation (LOQ) of 0.001mg/kg and retention time of 2.6 min. The half-lives of fluopyram in cucumber was 2.6~6.7d, indicated it was an easily digestible pesticide. The final levels of fluopyram was < LOQ~0.130mg/kg, which were lower than the maximum residue limit standard of China and the world. Probabilistic and deterministic models showed that fluopyram did not pose an unacceptable short-term dietary risk to Chinese dietary consumers (%ARfD, 0.081%~2.527%), whereas there was an unacceptable long-term dietary risk (%ADI, 105.740%~ 528.147%), of which cucumber accounted for 0.325%~1.107%. In addition, the long-term dietary risks of children aged 2~6 years (367.156%~528.147%) were significantly higher than that of other age groups (334.940%~105.740%) (p＜0.05). In summary, we should further focus on the negative effects of fluopyram exposure under multiple exposure pathways and joint risk amplification in the follow-up study, especially for vulnerable children.
韩文浩, 张明浩, 刘凤娇, 陈艺夫, 程有普, 吴艳兵, 陈增龙. 基于氟吡菌酰胺残留量概率分布评估膳食风险[J]. 中国环境科学, 2024, 44(5): 2714-2723.
HAN Wen-hao, ZHANG Ming-hao, LIU Feng-jiao, CHEN Yi-fu, CHENG You-pu, WU Yan-bing, CHEN Zeng-long. Dietary risk assessment based on the probability distribution of fluopyram residues. CHINA ENVIRONMENTAL SCIENCECE, 2024, 44(5): 2714-2723.
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